Permanent Present Tense Free download ↠ 5

Free read ´ PDF, eBook or Kindle ePUB free · Suzanne Corkin

In 1953 27 year old Henry Gustave Molaison underwent an experimental psychosurgical procedure a targeted lobotomy in an effort to alleviate his debilitating epilepsy The outcome was unexpected when Henry awoke he could no longer form new memories and for the rest of his life would be trapped in the moment But Henry’s tragedy would prove a gift to humanity As renowned neuroscientist Suzanne Corkin explains in Permanent Present Tense she and her colleagues brought to light the sharp contrast between Henry’s crippling memory impairment and his preserved intellect This new insight that the capacity for remembering is housed in a specific brain area revolutionized the science of memory The ca. 'Why Sir if you have but one book with you upon a journey let it be a book of science When you read through a book of entertainment you know it and it can do no for you but a book of science is inexhaustible'This uote of Samuel Johnson’s was recorded by his Scottish friend James Boswell in his book'Journal of a Tour to the Hebrides' published in 1785 a year after Johnson’s death Suzanne Corkin’s new biography of Henry Molaison the man with no memory is a fitting example of Johnson’s wise uote' Permanent Present Tense The Unforgettable Life of Amnesic Patient HM' Basic Books New York 2013 has been eagerly anticipated since the news leaked out that Dr Corkin had begun writing the life story of her most famous patient HM shortly after his death in December 2008 Corkin met HM in 1962 on his only visit to the Montreal Neurological Institute Her supervisor Dr Brenda Milner a neuropsychologist and neurosurgeon Dr Wilder Penfield both from the Montreal Neurological Institute were the first to realize that the experimental brain operation performed by William Scoville on 27 year old HM in an effort to cure his epilepsy had rendered him amnesic His seizures were almost vanuished but he would never again be able to make new conscious declarative memories In 1966 at the age of 40 HM —as he was known until after his death—made his first of 55 visits to the Clinical Research Center at MIT in Boston not far from where he lived in Hartford Connecticut Corkin was now a research scientist at MIT and “inherited” HM partly because of the ready access of MIT to Hartford In Dr Corkin’s lab Henry was the subject of thousands of experiments on memory and other cognitive abilities When HM had his surgery it was not known that the hippocampus the structures underlying the temporal lobes on each side of the brain were essential for forming new long term memories The studies on Henry have not only taught us about memory processes and the brain substrates underlying them but have stimulated and inspired countless students and researchers to pursue careers in neuroscience The way in which temporal lobe epilepsy is surgically treated also changed as a result of the experimental surgery performed on HM In his case the hippocampus was removed from both sides of his brain; we now know that if just one hippocampus is removed leaving a healthy structure on the other side temporal lobe seizures can be cured without the patient becoming amnesic When 82 year old Henry died in 2008 Dr Corkin had been working with him for 46 years yet he still didn’t know who she was When told her name was Suzanne he could say ‘Corkin’ but this was a superficial association of words rather than a signal that he knew her Corkin’s book is a science book in that it tells the fascinating story of memory and the methods experiments and technologies developed in order to understand it; it is a history book in that it draws the reader into the lives of the neuroscience researchers allowing us a peek into their thinking; it is a human story of the special relationship between researcher and patient; and it is a memoir about the man who did not lose his intelligence sense of humor or generosity when he lost his memory For me as one of the privileged few who worked with Henry when I was a postdoctoral fellow in Corkin’s lab reading this book was like a walk through the pa

review Permanent Present Tense

Permanent Present TenseSe of Henry known only by his initials H M until his death in 2008 stands as one of the most conseuential and widely referenced in the spiraling field of neuroscience Corkin and her collaborators worked closely with Henry for nearly fifty years and in Permanent Present Tense she tells the incredible story of the life and legacy of this intelligent uiet and remarkably good hud man Henry never remembered Corkin from one meeting to the next and had only a dim conception of the importance of the work they were doing together yet he was consistently happy to see her and always willing to participate in her research His case afforded untold advances in the study of memory including the discovery t. This book tells the story of a 27 year old patient HM who in 1953 underwent experimental surgery to relieve the effects of a severe case of epilepsy An unintended conseuence of the operation however was the loss of the capacity to form long term memories of any experience after the operation While the real situation in the case had complexities the basic problem was that whatever HM experienced he lost about 30 seconds later He could not transform his experience into memories that contribute to personality identity and an orientation to the world HM was perpetually stuck in the present hence the title of the bookThe story gets interesting The case is brought to the attention of researchers who are studying the brain and memory and they see this patient as providing an opportunity for very important research HM's conditions allows the scientists to test their theories on how we remember experience what we retain what type of learning takes place at what location in the brain and a host of other problems This patient's case combined a clearly identified brain disorder and the ability to talk about it take tests and be a continuing subject in a study This case is one of a very few that permit the physical study of the brain to be studied in conjunction with the cognitive psychology studies of the individual suffering the disability HM provided a once in a lifetime opportunity to advance research settle conflicting theories and help in the understanding of brain disorders such as Alzheimer's Parkinson's Disease Huntingdon's disease and various forms of dementia The author Suzanne Corkin ran the lab at MIT through which much of this research took place and studied this patient for fifty years By the time HM died the author knew about him that anyone else aliveThe interaction of the personal tragedy and the research triumph would be enough to make a good story At the same time the author uses the book to provide a fantastic account of how the research uestions raised by this case developed how the studies were designed and how new lines of inuiry were suggested by prior research The book provides a wonderful history of neuroscience and an exciting account of how research develops in a hot area of neuroscience There are few popular accounts of scientific activity that match this account of how the field developed through its interaction with HM as a perpetual test subjectThe book is not without contradictions and issues What happened to HM is horrible and gives cause for uestioning just what he experienced for those fifty years At the same time HM's tragedy was certainly a boon to neuroscience and the success of this research stream made careers brought fame to many drew new scientists into the area and most likely was good for raising money as well All that is fine but a what cost The neurosurgeon who conducted the operation disappears from the narrative early on but not without noting that what he did was a big mistake The author clearly took her relationship with HM very seriously and worked to ensure his welfare At the same time it is impossible not to note the planning that went into managing how to make the best use of HM's body once he died It is also clear that important careers were made studying this man's life with his horrible man made condition It is difficult to see how that tension is effectively managed and balanced I see

Suzanne Corkin · 5 Summary

Permanent Present Tense Free download ↠ 5 ↠ In 1953 27 year old Henry Gustave Molaison underwent an experimental psychosurgical procedure—a targeted lobotomy—in an effort to alleviate his debilitating epilepsy The outcome was unexpected—when Henry awoke he could no longer form new memories and for the rest of his life would be traHat even profound amnesia spares some kinds of learning and that different memory processes are localized to separate circuits in the human brain Henry taught us that learning can occur without conscious awareness that short term and long term memory are distinct capacities and that the effects of aging related disease are detectable in an already damaged brainUndergirded by rich details about the functions of the human brain Permanent Present Tense pulls back the curtain on the man whose misfortune propelled a half century of exciting research With great clarity sensitivity and grace Corkin brings readers to the cutting edge of neuroscience in this deeply felt elegy for her patient and frie. I had really hoped to enjoy this book I am a medical researcher myself and much of my work has been informed by the exciting studies that were first illuminated by HM Still I found the writing to be drab and textbook like Much of the book was split between Corkin highlighting her own work and defensively explaining her use of Henry Molaison her experiments She somehow argues that HM 'only' made up 22% of the work that came out of her lab There is a mix of a sad story about the trajectory of HM's life along with the advances made possible by his participation in studies Unfortunately this is not the most interesting place to read that story